Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
The Effect of Black Seeds (Nigella Sativa) on Prediabetic Overweight and Obese Adolescents	Imam Abdulrhman bin Faisal university	Ongoing	Nigella sativa seeds	3	2230500005	Family and Community Medicine Center (Dammam)
A Randomized, Double Blinded, Comparative Observational Interventional Study to Assess The Safety And Immunogenicity Of Hepatitis B Vaccine In Newborns / Adolescents And Adults Six Months Post Vaccination	Arab Company for Pharmaceutical products	Ongoing	EUVAX B VACCINE	4	HBV-001	King Fahad Medical City (Riyadh)
Impact of using Zinc Oxide versus Moist Exposed Wound Ointment (MEBO) in treatment of second stage pressure ulcer: A randomized control clinical trial	King Abdullah Medical City (Makkah)	Ongoing	MEBO and Zinc oxide topical	3	Version 5	King Abdullah Medical City (Makkah)
A Proof of Concept, Phase IIa, Open Label Study to Evaluate the Safety and Efficacy of Subcutaneous Implants of Afamelanotide in Patients with Xeroderma Pigmentosum (XP)	CLINUVEL EUROPE LIMITED	Ongoing	Afamelanotide	2a	CUV156	King Faisal Specialist Hospital and Research Center (Riyadh)
A randomized, double-blind, double-dummy, parallel-group study, comparing the efficacy and safety of remibrutinib versus teriflunomide in participants with relapsing multiple sclerosis, followed by extended treatment with open-label remibrutinib	Novartis	Ongoing	remibrutinib	3	CLOU064C123	King Faisal Specialist Hospital and Research Center (Jeddah) - King Abdulaziz Medical City NG (Jeddah) - King Abdulaziz Medical City NG (Riyadh)
An Open-label Extension Trial to Evaluate the Long-term Safety of KVD900, an Oral Plasma Kallikrein Inhibitor, for On-demand Treatment of Angioedema Attacks in Adolescent and Adult Patients with Hereditary Angioedema Type I or II	KalVista Pharmaceuticals Ltd	Ongoing	Sebetralstat	3	KVD900-302	King Faisal Specialist Hospital and Research Center (Riyadh)
A prospective observational international study of cabozantinib tablets in combination with nivolumab as first-line treatment of advanced renal cell carcinoma in adults	Ipsen Pharma	Ongoing	Cabozantinib	4	CLIN-60000	King Abdulaziz Medical City NG (Riyadh)
A Phase 3, Randomized, Placebo-controlled, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Guselkumab in Participants with Fistulizing, Perianal Crohn’s Disease	Janssen Research & Development LLC	Ongoing	Guselkumab	3	CNTO1959CRD3005	King Faisal Specialist Hospital and Research Center (Riyadh), King Fahad Specialist Hospital (Dammam), King Saud Medical City (Riyadh), King Abdulaziz Medical City NG (Jeddah)
A Randomized, Double-blind, Multicenter Study to Determine the Effect of Triheptanoin Compared with Even-chain, Medium-chain Triglycerides (MCT) on Major Clinical Events (MCEs) in Pediatric Patients with Long-chain Fatty Acid Oxidation Disorders (LC-FAOD)	Ultragenyx Pharmaceutical Inc	Ongoing	UX007/triheptanoin, Medium-chain Triglycerides (MCT),Dextrose. Monosaccharide. Blood Glucose-Elevating Agents.	3	UX007-CL30	King Faisal Specialist Hospital and Research Center (Riyadh)
A Phase III, Randomized, Open-Label, Sponsor-Blinded, Multicenter Study of Durvalumab in Combination with Tremelimumab ± Lenvatinib Given Concurrently with Transarterial Chemoembolization (TACE) Compared to TACE Alone in Patients with Locoregional Hepatocellular Carcinoma (EMERALD-3)	AstraZeneca	Ongoing	Lenvatinib (Lenvima) + Durvalumab (Imfinzi) + Tremelimumab (Imjudo)	3	D910VC00001	King Faisal Specialist Hospital and Research Center (Riyadh) ,King Abdulaziz Medical City NG (Jeddah), King Fahad Specialist Hospital (Dammam), King Abdulaziz Medical City NG (Riyadh)