Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
A Phase 2 Open-label, Dose Escalation Study of HST5040 in Subjects with Propionic or Methylmalonic Acidemia Followed by a 6-Month, Randomized, Double-blind, Placebo-controlled, 2-period Crossover Study and an Open-label, Long-term Extension Study	HemoShear Therapeutics,	Terminated	ST5040 (2,2-dimethylbutanoic acid)	4	HST20-CL01	King Faisal Specialist Hospital and Research Center (Riyadh)
An observational disease and clinical outcomes registry of patients with acid lipase (LAL) deficiency	Alexion Pharma	Ongoing	Kanuma	4	ALX-LALD-5	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz Medical City NG (Riyadh)
A study comparing the effect and safety of once weekly dosing of somapacitan with daily Norditropin® as well as evaluating long-term safety of somapacitan in a basket study design in children with short stature either born small for gestational age or with Turner syndrome, Noonan syndrome, or idiopathic short stature	Novo Nordisk	Ongoing	Sogroya , Norditropin	3	NN8640-4467	King Faisal Specialist Hospital and Research Center (Riyadh) , King Abdulaziz Medical City NG (Riyadh)
Early Sedation with Dexmedetomidine vs. Placebo in Older Ventilated Critically Ill Patients A Prospective, Multi-Centre, Double-Blind, Randomized, Controlled Trial. SPICE IV	King Abdullah International Medical Research Center (KAIMRC)	Ongoing	DEXMEDETOMIDINE	4	SCT21R/006/04	King Abdulaziz Medical City NG (Riyadh), King Faisal Specialist Hospital and Research Center (Riyadh)
VICTORION REAL: An international prospective Real-world study to evaluate the Effectiveness and Adherence of incLisiran plus standard of care lipid-lowering therapy compared to standard of care therapy alone in patients with primary hypercholesterolemia or mixed dyslipidemia	Novartis	Ongoing	Inclisiran	4	CKJX839A12	Saud Al-Babtain Cardiac Center (Dammam) , King Salman Armed Forces Hospital(Tabuk) , King Fahd Armed Forces Hospital (Jeddah) , Dr. Sulaiman Al-Habib Medical Group Rayan (Riyadh),King Faisal Specialist Hospital and Research Center (Jeddah), Dr. Sulaiman Al-Habib Medical Group Olaya (Riyadh), International Medical Center (Jeddah)
The effect of novel D3 use as a mouthwash in COVID-19 patients	King Faisal Specialist Hospital and Research Center (Jeddah)	Rejected	D3 mouthwash	4	2022-32	King Faisal Specialist Hospital and Research Center (Jeddah)
O-SEMA-Fast: A research study to understand how oral semaglutide works in people with type 2 diabetes who plan to fast during Ramadan in the United Arab Emirates, Saudi Arabia, and Kuwait	Novo Nordisk	Ongoing	Semaglutide	4	NN9924-757	Almoosa Specialist Hospital (Alahsa)
Study on Clinical Use of EVUSHELD (AZD7442) as Pre-exposure Prophylaxis in the Real-world Setting – A Multi-centre Observational Prospective Study to Determine the Utilisation and Clinical Outcomes of EVUSHELD in Middle East and Africa	AstraZeneca	Ongoing	EVUSHELD	4	D8851R0000	King Saud Medical City (Riyadh)
A REGISTRY TO COLLECT CHARACTERISTICS AND OUTCOMES FROM PATIENTS WITH SOLID TUMORSPROFILED WITH A NEXT-GENERATION SEQUENCINGTEST (WAYFIND-R)	Roche	Ongoing	NA	4	MX39897	King Abdulaziz Medical City NG (Riyadh)
Real-World Experience of Upadacitinib in Moderate to Severe Atopic Dermatitis	Abbvie	Ongoing	Upadacitinib (Rinvoq)	4	H23-107	King Faisal General Hospital (Makkah), Mohammed Dossary Hospital - Al Khobar, King Fahad Central Hospital (Jazan), East Jeddah General Hospital, Hira Hospital (Makkah) , Aseer Central Hospital (Abha)