Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
A phase II, multicenter, open label study of treatment escalation to ACVD (Adriamycin, Cyclophosphamide, Vinblastine and Dacarbazine) and Brentuximab-Vedotin in advanced-stage Hodgkin Lymphoma patients with a positive interim PET scan after 2 ABVD cycles (OPTIMIST study)	KAIMRC	Ongoing	DOXORUBICIN HYDROCHLORIDE	2	RC16/150	NGHA-R
A Phase II Study to examine the efficacy and safety of a new drug called Sevuparin on resolution of painful vaso-occlusive crisis in patients with sickle-cell disease.	Modus Therapeutics AB	Ongoing	Sevuparin	3	TVOC01	KKUH
A phase II randomized study of the combination of Ribociclib plus goserelin acetate with Hormonal Therapy versus physician choice chemotherapy in premenopausal or perimenopausal patients with hormone receptorpositive/HER2-negative inoperable locally advanced or metastatic breast cancer – RIGHT Choice Study.	Novartis	Terminated	ribociclib	2	CLEE011A3201C	King Faisal Specialist Hospital and Research Center (Riyadh)
"A Phase II open-label, single-arm, multi-center study of ruxolitinib added to corticosteroids in pediatric subjects with moderate and severe chronic graft vs. host disease after allogeneic stem cell transplantation"	Novartis	Completed	ruxolitinib	2	CINC424G12201	KFSH&RC-R
A Phase Ib study to determine the safety and immunogenicity of the candidate Middle East Res-piratory Syndrome Coronavirus (MERS-CoV) vaccine ChAdOx1 MERS in healthy adult Middle Eastern volunteers	KAIMRC	Ongoing	vaccine ChAdOx1 MERS	1b	CT18/004/R	NGHA-R
"A Phase 3B, Randomized, Double-Blind Clinical Trial to Evaluate the Efficacy and Safety of Abatacept SC in Combination with Methotrexate Compared to Methotrexate Monotherapy in Achieving Clinical Remission in Adults with Early Rheumatoid Arthritis who are Methotrexate Naive"	Bristol-Myers Squibb	Terminated	Abatacept	3b	IM101550	KFMC
A Phase 3b, open-labeled, randomized, parallel-group, multi-center study to evaluate the safety of novartis MenACWY Conjugate Vaccine when administered with routine infant Vaccinations to healthy Infants	Novartis	Completed	Meningococcal ACWY Conjugate Vaccine	3b	V59P23	KFMC
A Phase 3, Randomized, Multi-center, Open-label Study of Trastuzumab Deruxtecan (T-DXd) Versus Investigator’s Choice Chemotherapy in HER2-low, Hormone Receptor Positive Breast Cancer Patients whose Disease has Progressed on Endocrine Therapy in the Metastatic Setting (DESTINY-Breast06)	Astrazeneca	Ongoing	Trastuzumab Deruxtecan	3	D9670C00001	King Fahad Medical City (Riyadh)
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multinational Clinical Study to Evaluate the Efficacy and Safety of 2.0 mg/kg/Week and 2.0 mg/kg/Every Other Week BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)	BioMarin Pharmaceutical Inc.	Completed	BMN 110	3	MOR-004	KFSH & RC-R
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Voxelotor (GBT440) in Pediatric Participants with Sickle Cell Disease (HOPE Kids 2)	Sponsor (Global Blood Therapeutics, Inc.)	Ongoing	Voxelotor (GBT440)	3	GBT440-032	King Khalid University Hospital (Riyadh)