Drug Clinical Trials List

Study Title	Study Sponsor	Status	Study Drug	Trial Phase	Study Protocol Number	Site
Transthyretin Amyloidosis Outcomes Survey (THAOS): A Global, Multi-Center, Longitudinal, Observational Survey of Patients With Documented Transthyretin Gene Mutations or Wild-Type Transthyretin Amyloidosis	Pfizer	Terminated	Tafamidis	4	B3461001	King Faisal Specialist Hospital and Research Center (Riyadh)
A Phase 2/3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Mitapivat in Subjects With Sickle Cell Disease	Agios Pharmaceuticals, Inc.	Ongoing	Mitapivat	2/3	AG348-C-020	King Khalid University Hospital (Riyadh)
Prospective, observational study in sickle cell disease patients on crizanlizumab treatment in Middle East countries and India.	Novartis	Ongoing	crizanlizumab	4	CSEG101AIC05	Prince Mohammad Bin Naser Hospital, Jizan, Saudi Arabia
A PHASE II, SINGLE-ARM STUDY OF ATEZOLIZUMAB IN PATIENTS WITH LOCALLY ADVANCED, UNRESECTABLE STAGE III NON-SMALL CELL LUNG CANCER WHO HAVE NOT PROGRESSED AFTER PLATINUM-BASED CONCURRENT CHEMORADIATION	Roche	Ongoing	ATEZOLIZUMAB (TECENTRIQ)	2	MO43156	King Fahad Specialist Hospital (Dammam)
A randomized, sham-controlled, double-blind study to evaluate the efficacy and safety of intrathecal (IT) OAV101 in patients with later onset Type 2 spinal muscular atrophy (SMA) who are ≥ 2 to < 18 years of age, treatment naive, sitting, and never ambulatory	Novartis Saudi Limited	Ongoing	OAV101 (formerly AVXS-101)	3	COAV101B12301	King Faisal Specialist Hospital and Research Center (Riyadh),King Fahad Specialist Hospital (Dammam)
Timing Of Thyroxine Dose In Ramadan	KAIMRC	Ongoing	Levothyroxine	4	ICT22J/001	King Abdulaziz Medical City NG (Jeddah)
Fluids in septic shock (FISSH)	KAIMRC	Ongoing	RINGER'S-LACTATE SOLUTION	3	SCT21R/001/01	King Abdulaziz Medical City NG (Riyadh)
Phase II study of neoadjuvant hormonal therapy guided by interval Ki67 testing in hormonal receptor-positive, HER2-negative breast cancer.	King Abdullah Medical City (Makkah)	Ongoing	Letrozole (Femaplex)	2	20-718	King Abdullah Medical City (Makkah)
Modern Treatment of Inhibitor-PositiVe PATiEnts with Haemophilia A – An International Low-Interventional Pragmatic Investigator Initiated Trial	Octapharma AG	Ongoing	Octanate, Wilate, Hemlibra, NovoSeven, Feiba	4	MOTIVATE	King Abdulaziz Medical City NG (Riyadh)
Phase 1b/2 Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia	Onyx Therapeutics, Inc., an Amgen Inc. Subsidiary	Ongoing	Carfilzomib	2	20140106	King Fahad Medical City (Riyadh)