Rama is the Director, Medical Devices in the Medical Devices Cluster of the Health Sciences Authority (HSA). She oversees pre-market registration and post-market controls for all medical devices in Singapore. She also oversees the device development consultation that aims to support safe innovation in medical technologies locally. She has been working in Medical Device Regulations for over 13 years now. She currently represents Singapore as a member of the Management Committee of the International Medical Device Regulators Forum (IMDRF). She is also the current head of delegation for Singapore in the ASEAN Medical Device Committee (AMDC).

Prior to joining the HSA, she was involved in Research on chronic pain and neuropathic pain at the National University of Singapore, identifying novel biomarkers related to pain and developing novel diagnostic methods using principles of chemistry in analysis of biological samples.